NXPZ-2
| Specifications | |
|---|---|
| CAS Number: | 2254492-08-3 |
| Formula: | C27H27N5O7S2 |
| Molecular Weight: | 597,66 |
Description
NXPZ-2 is an orally active Keap1-Nrf2protein-protein interaction (PPI) inhibitor (Ki: 95 nM, EC50: 120 and 170 nM). NXPZ-2 dose-dependently attenuates Aβ[1-42]-induced cognitive disturbances, enhances neuronal number and function, and enhances pathological alterations in the brain of Alzheimer's disease (AD) mice.NXPZ-2 has potential for studies of Keap1-Nrf2 PPI inhibitors and AD-related disorders.
Price
1.522,00 €
