siRNA Constructs
Lentiviral and AAV siRNA Cloning and Expression Constructs
Streamline your cloning and knockdown of target genes
RNAi Expression System
Clone and express any siRNA using the specially-designed RNAi Expression System for Lentivirus and AAV. The System is based on a unique convergent promoter design for efficient gene knockdown, without the need for a hairpin loop structure. It includes a GFP reporter for transduction monitoring and offers a comprehensive library of human, mouse, and rat siRNAs in Lentivirus and AAV (serotypes 1–11) vector formats for tissue-specific knockdown. A pre-packaged virus format can be delivered on request.
- Utilizes potent 27-29 bp oligos than traditional 19 or 21 bp oligos
- Convergent promoters to avoid hairpin loop structures, making sequencing and plasmid growth much easier
- GFP reporter for real time monitoring of transfection or viral infection
- Available as a set of 4 lenivirus or 3 AAV constructs for enhanced gene knockdown
- AAV delivery results in low immunogenicity and no genomic integration
Questions?
Connect with us today to get started with the RNAi Expression System.
