TMX-4153
| Specifications | |
|---|---|
| CAS Number: | 2867519-91-1 |
| Formula: | C59H67ClN10O6S |
| Molecular Weight: | 1079,75 |
Description
TMX-4153 is a bivalent degrader that selectively targets and rapidly degrades endogenous PIP4K2C through recruitment of the von Hippel-Lindau (VHL) E3 ligase complex, demonstrating a K D of 42 nM. It is applicable in the synthesis of PROTAC [1].
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