Timp1 Polyclonal Antibody, FITC Conjugated
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Clonality: | Polyclonal |
| Host: | Rabbit |
| Reactivity: | Rat |
| Isotype: | IgG |
| Label: | FITC |
| Additional Information | |
|---|---|
| Synonyms: | Tissue inhibitor of metalloproteinases 1, TIMP-1, Timp1, Timp-1 |
| UniProt ID: | P30120 |
Applications
ELISA
Recommended Dilution
Recommended dilution: ELISA 1:100-1:500
Immunogen
Recombinant Rat Metalloproteinase inhibitor 1 protein (24-217AA)
Purification/Format
Protein G purified
Background
Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Also stimulates steroidogenesis by Leydig and ovarian granuloma cells; procathepsin L is required for maximal activity.
Price
472,00 €
