RIN1 Polyclonal Antibody, FITC Conjugated
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Clonality: | Polyclonal |
| Host: | Rabbit |
| Reactivity: | Human |
| Isotype: | IgG |
| Label: | FITC |
| Additional Information | |
|---|---|
| Synonyms: | Ras and Rab interactor 1, Ras inhibitor JC99, Ras interaction/interference protein 1, RIN1 |
| UniProt ID: | Q13671 |
Applications
ELISA
Recommended Dilution
Recommended dilution: ELISA 1:100-1:500
Immunogen
Recombinant Human Ras and Rab interactor 1 protein (192-341AA)
Purification/Format
Protein G purified
Background
Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.
Price
475,00 €
