Rabbit anti-Phospho-Glucocorticoid Receptor (Ser211) Polyclonal Antibody

Specifications
Type:Primary Antibody
Clonality:Polyclonal
Host:Rabbit
Reactivity:Human, Mouse, Rat
Isotype:IgG
Label:Unconjugated
Concentration:1 mg/mL
Buffer:PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Additional Information
Synonyms:GCCR, GCR, GCR, GCRST, glucocorticoid nuclear receptor variant 1, Glucocorticoid receptor, GR, GRL, Grl1, nr3c1, Nuclear receptor subfamily 3 group C member 1, nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
Gene Symbol:NR3C1
Organism:Homo sapiens
Gene ID:2908
UniProt ID:P04150

Applications

WB, IHC-p, ELISA

Recommended Dilution

WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000

Immunogen

Synthesized peptide derived from human GR around the phosphorylation site of Ser211

Purification/Format

Affinity purification

Background

Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. Plays a significant role in transactivation. Involved in nuclear translocation.
Price
916,00 €
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