Rabbit anti-Phospho-EEF2K (Ser366) Polyclonal Antibody

Specifications
Type:Primary Antibody
Clonality:Polyclonal
Host:Rabbit
Reactivity:Human, Rat
Isotype:IgG
Label:Unconjugated
Concentration:1 mg/mL
Buffer:PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Additional Information
Synonyms:C86191, Calcium/calmodulin dependent eukaryotic elongation factor 2, Calcium/calmodulin dependent eukaryotic elongation factor 2 kinase, Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase, Calmodulin dependent protein kinase III, cb365, EC 2.7.11.20, eEF 2 kinase, eEF 2K, eEF-2 kinase, eEF-2K, Eef2k, EEF2K protein, EF2K, Elongation factor 2 kinase, Eukaryotic elongation factor 2 kinase, fa04b08, HSU93850, kinase eEF2K, MGC45041, SMEF2K, wu:fa04b08, zgc:100973
Gene Symbol:EEF2K
Organism:Homo sapiens
Gene ID:29904
UniProt ID:O00418

Applications

WB, IHC-p, ELISA

Recommended Dilution

WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000

Immunogen

Synthesized peptide derived from human eEF2K around the phosphorylation site of Ser366

Purification/Format

Affinity purification

Background

This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment.
Price
314,00 €
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