Rabbit anti-MRE11 Polyclonal Antibody
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Clonality: | Polyclonal |
| Host: | Rabbit |
| Reactivity: | Human, Mouse, Rat |
| Isotype: | IgG |
| Label: | Unconjugated |
| Concentration: | 0.5 mg/mL |
| Buffer: | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Additional Information | |
|---|---|
| Synonyms: | AT like disease, Ataxia telangiectasia disorder like, ATLD, DNA recombination and repair protein, Double strand break repair protein MRE11A, Double-strand break repair protein MRE11A, endo/exonuclease Mre11, HNGS1, meiotic recombination (S. cerevisiae) 11 homolog A, Meiotic recombination 11 homolog 1, meiotic recombination 11 homolog A (S. cerevisiae), Meiotic recombination 11 homolog A, MmMRE11A, Mre 11, MRE 11a, MRE 11b, MRE11 homolog 1, MRE11 homolog A, MRE11 homolog double strand break repair nuclease, MRE11 meiotic recombination 11 homolog A (S. cerevisiae), MRE11 meiotic recombination 11 homolog A, MRE11, MRE11A, MRE11b, OTTHUMP00000236830, OTTHUMP00000236831, OTTHUMP00000236832, OTTHUMP00000236833 |
| UniProt ID: | P49959 |
Applications
IHC, ELISA
Recommended Dilution
IHC 1:100-1:300
Immunogen
Recombinant protein of human MRE11A
Purification/Format
Affinity purification
Background
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
- Catalog Number
RD78250A-20-RDB - Supplier
Reddot Biotech - Size
- Shipping
Blue Ice
Price
314,00 €
