Rabbit anti-IDH2 Polyclonal Antibody
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Clonality: | Polyclonal |
| Host: | Rabbit |
| Reactivity: | Human, Mouse, Rat |
| Isotype: | IgG |
| Label: | Unconjugated |
| Concentration: | 0.4 mg/mL |
| Buffer: | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Additional Information | |
|---|---|
| Synonyms: | D2HGA2, ICD-M, IDH, IDH2, IDHM, IDHP, IDP, IDPM, Isocitrate dehydrogenase [NADP], mitochondrial, Isocitrate dehydrogenase 2 (NADP+), mitochondrial, mNADP-IDH, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase |
| UniProt ID: | P48735 |
Applications
WB, IHC, ELISA
Recommended Dilution
WB 1:500-1:2000, IHC 1:100-1:300
Immunogen
Recombinant protein of human IDH2
Purification/Format
Affinity purification
Background
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.
- Catalog Number
RD78174A-20-RDB - Supplier
Reddot Biotech - Size
- Shipping
Blue Ice
Price
314,00 €
