Rabbit anti-EIF2 alpha Polyclonal Antibody

Specifications
Type:Primary Antibody
Clonality:Polyclonal
Host:Rabbit
Reactivity:Human, Mouse, Rat, Monkey
Isotype:IgG
Label:Unconjugated
Concentration:1 mg/mL
Buffer:PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Additional Information
Synonyms:EIF 2 alpha, EIF 2, EIF 2A, EIF 2alpha, eIF-2-alpha, eIF-2A, EIF-2alpha, EIF2 alpha, EIF2, EIF2A, EIF2S1, Eukaryotic translation initiation factor 2 subunit 1 alpha 35kDa, Eukaryotic translation initiation factor 2 subunit 1 alpha, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit alpha, IF2A
Gene Symbol:EIF2S1
Organism:Homo sapiens
Gene ID:1965
UniProt ID:P05198

Applications

WB, IHC-p, IF, ELISA

Recommended Dilution

WB 1:500-1:2000, IHC 1:100-1:300, IF 1:50-1:200, ELISA 1:10000

Immunogen

Synthesized peptide derived from human eIF2α around the non-phosphorylation site of Ser51.

Purification/Format

Affinity purification

Background

Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins.
Price
314,00 €
you need any help?

Please contact:

Dr. Simone Bauer

Tel. +49 (0) 6221 71415 16

info@biocat.com

Image