Rabbit anti-ALDH3A1 Polyclonal Antibody

Specifications
Type:Primary Antibody
Clonality:Polyclonal
Host:Rabbit
Reactivity:Human, Mouse, Rat
Isotype:IgG
Label:Unconjugated
Concentration:0.4 mg/mL
Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Additional Information
Synonyms:Acetaldehyde dehydrogenase 3, AHD 4, AHD C, AHD4, AHDC, AL3A1, Aldehyde dehydrogenase 3, Aldehyde dehydrogenase 3 family member A1, Aldehyde dehydrogenase 3A1, Aldehyde dehydrogenase, Aldehyde dehydrogenase class 3, Aldehyde dehydrogenase dimeric NADP preferring, Aldehyde dehydrogenase family 3 member A1, Aldehyde dehydrogenase family 3 subfamily A1, Aldehyde dehydrogenase family 3, subfamily A, member 1, Aldehyde dehydrogenase isozyme 3, Aldehyde dehydrogenase type III, ALDH 3, ALDH 3A1, ALDH III, ALDH, stomach type, ALDH3 A1, ALDH3, ALDH3A 1, Aldh3a1, ALDHIII, dimeric NADP-preferring, MGC10406, Stomach aldehyde dehydrogenase, Tumor associated aldehyde dehydrogenase tumor ALDH
UniProt ID:P30838

Applications

WB, IHC, ELISA

Recommended Dilution

WB 1:500-1:2000, IHC 1:50-1:200

Immunogen

Recombinant protein of human ALDH3A1

Purification/Format

Affinity purification

Background

Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Price
314,00 €
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