Rabbit anti-AKAP12 Polyclonal Antibody

Specifications
Type:Primary Antibody
Clonality:Polyclonal
Host:Rabbit
Reactivity:Human
Isotype:IgG
Label:Unconjugated
Concentration:0.4 mg/mL
Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Additional Information
Synonyms:A kinase (PRKA) anchor protein (gravin) 12, A kinase Anchor Protein 12, A kinase anchor protein 250kDa, A-kinase anchor protein 12, A-kinase anchor protein 250 kDa, AKA12, AKAP 12, AKAP 250, AKAP-12, Akap12, AKAP250, DKFZp686M0430, DKFZp686O0331, FLJ20945, FLJ97621, Gercelin, Gravin, Kinase scaffold protein gravin, Myasthenia gravis autoantigen, Myasthenia gravis autoantigen gravin, OTTHUMP00000017426, OTTHUMP00000017427, Src-Suppressed C Kinase Substrate, Srcs5, SSeCKS, Tsga12
UniProt ID:Q02952

Applications

IHC, ELISA

Recommended Dilution

IHC 1:50-1:200

Immunogen

Synthetic peptide of human AKAP12

Purification/Format

Affinity purification

Background

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Price
314,00 €
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