Rabbit anti-AK2 Polyclonal Antibody

Specifications
Type:Primary Antibody
Clonality:Polyclonal
Host:Rabbit
Reactivity:Human, Mouse, Rat
Isotype:IgG
Label:Unconjugated
Concentration:0.2 mg/mL
Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Additional Information
Synonyms:Adenylate kinase 2, adenylate kinase 2, mitochondrial, Adenylate kinase isoenzyme 2, ADK2, AK 2, ak2, ATP AMP transphosphorylase, ATP-AMP transphosphorylase 2, EC 2.7.4.3, KAD2, mitochondrial
UniProt ID:P54819

Applications

WB, IHC, ELISA

Recommended Dilution

WB 1:500-1:2000, IHC 1:50-1:200

Immunogen

Recombinant protein of human AK2

Purification/Format

Affinity purification

Background

Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2.
Price
314,00 €
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