Rabbit anti-AIMP1 Polyclonal Antibody

Specifications
Type:Primary Antibody
Clonality:Polyclonal
Host:Rabbit
Reactivity:Human, Mouse
Isotype:IgG
Label:Unconjugated
Concentration:0.6 mg/mL
Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Additional Information
Synonyms:AIMP 1, Aimp1, AIMP1/p43, AIMP1, Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1, ARS interacting multifunctional protein 1, EMAP 2, EMAP-2, EMAP-II, EMAP2, EMAPII, Endothelial monocyte activating polypeptide 2, Endothelial monocyte activating polypeptide, Endothelial monocyte-activating polypeptide 2, Endothelial monocyte-activating polypeptide II, HLD3, Multisynthase complex auxiliary component p43, Multisynthetase complex auxiliary component p43, OTTHUMP00000219673, p43, Scye 1, Scye1, Scye1, formerly, Small inducible cytokine subfamily E member 1, Small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating), Small inducible cytokine subfamily E, member 1, formerly
UniProt ID:Q12904

Applications

WB, IHC, ELISA

Recommended Dilution

WB 1:500-1:2000, IHC 1:50-1:200

Immunogen

Synthetic peptide of human AIMP1

Purification/Format

Affinity purification

Background

The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20.
Price
314,00 €
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