Rabbit anti-AIF1 Polyclonal Antibody
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Clonality: | Polyclonal |
| Host: | Rabbit |
| Reactivity: | Mouse, Rat |
| Isotype: | IgG |
| Label: | Unconjugated |
| Concentration: | 1.6 mg/mL |
| Buffer: | PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4 |
| Additional Information | |
|---|---|
| Synonyms: | AIF 1, AIF-1, Aif1, AIF1 protein, AIF1, Allograft inflammatory factor 1, Allograft inflammatory factor 1 splice variant G, allograft inflammatory factor-1 splice variant Hara-1, balloon angioplasty responsive transcription, BART 1, G1, G1 putative splice variant of allograft inflamatory factor 1, IBA 1, IBA1, interferon gamma responsive transcript, Interferon responsive transcript 1, interferon responsive transcript factor 1, Ionized calcium binding adapter molecule 1, Ionized calcium-binding adapter molecule 1, ionized calcium-binding adapter molecule, IRT 1, IRT1, Microglia response factor, MRF1, Protein g1 |
| UniProt ID: | O70200, P55009 |
Applications
IHC
Recommended Dilution
IHC 1:200-1:800
Immunogen
KLH conjugated Synthetic peptide corresponding to HumanIBA-1
Purification/Format
Affinity purification
Background
This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Three transcript variants encoding different isoforms have been found for this gene.Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
Price
421,00 €
