Rabbit anti-AGRN Polyclonal Antibody
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Clonality: | Polyclonal |
| Host: | Rabbit |
| Reactivity: | Human |
| Isotype: | IgG |
| Label: | Unconjugated |
| Concentration: | 0.3 mg/mL |
| Buffer: | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Additional Information | |
|---|---|
| Synonyms: | AGRIN, Agrin proteoglycan, AGRN, FLJ45064, OTTHUMP00000044043 |
| UniProt ID: | O00468 |
Applications
IHC, ELISA
Recommended Dilution
IHC 1:25-1:100
Immunogen
Synthetic peptide of human AGRN
Purification/Format
Affinity purification
Background
This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in this gene was found.
- Catalog Number
RD78657A-20-RDB - Supplier
Reddot Biotech - Size
- Shipping
Blue Ice
Price
314,00 €
