Rabbit anti-ADRB2 Polyclonal Antibody

Specifications
Type:Primary Antibody
Clonality:Polyclonal
Host:Rabbit
Reactivity:Human, Mouse
Isotype:IgG
Label:Unconjugated
Concentration:0.3 mg/mL
Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Additional Information
Synonyms:ADRB2, ADRB2, ADRB2R, ADRBR, Adrenergic beta 2 receptor surface, Adrenoceptor beta 2 surface, B2AR, BAR, beta 2 adrenoceptor, Beta 2 adrenoreceptor, Beta-2 adrenergic receptor, Beta-2 adrenoceptor, Beta-2 adrenoreceptor, BETA2AR, Catecholamine receptor, OTTHUMP00000160386
UniProt ID:P07550

Applications

WB, ELISA

Recommended Dilution

WB 1:1000-1:2000

Immunogen

Synthetic peptide of human ADRB2

Purification/Format

Affinity purification

Background

This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.
Price
443,00 €
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