Rabbit anti-ACTA1 Polyclonal Antibody

Specifications
Type:Primary Antibody
Clonality:Polyclonal
Host:Rabbit
Reactivity:Human, Mouse, Rat
Isotype:IgG
Label:Unconjugated
Concentration:0.5 mg/mL
Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Additional Information
Synonyms:a actin, ACTA, ACTA1, Actin alpha skeletal muscle, Actin, actin, alpha 1, skeletal muscle 1, actin, alpha 1, skeletal muscle, Actin, alpha skeletal muscle, actina, actine, ACTS, aktin, Alpha Actin 1, Alpha skeletal muscle Actin, alpha skeletal muscle, alpha-actin, Alpha-actin-1, ASMA, CFTD, CFTD1, CFTDM, MPFD, NEM1, NEM2, NEM3, nemaline myopathy type 3
UniProt ID:P68133

Applications

WB, IHC, ELISA

Recommended Dilution

WB 1:500-1:2000, IHC 1:50-1:200

Immunogen

Recombinant protein of human ACTA1

Purification/Format

Affinity purification

Background

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
Price
602,00 €
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