Rabbit anti-ACMSD Polyclonal Antibody

Specifications
Type:Primary Antibody
Clonality:Polyclonal
Host:Rabbit
Reactivity:Human, Mouse
Isotype:IgG
Label:Unconjugated
Concentration:0.2 mg/mL
Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Additional Information
Synonyms:2 amino 3 carboxymuconate 6 semialdehyde decarboxylase, 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase, acmsd, ACMSD, Aminocarboxymuconate semialdehyde decarboxylase, Picolinate carboxylase
UniProt ID:Q8TDX5

Applications

WB, ELISA

Recommended Dilution

WB 1:500-1:2000

Immunogen

Recombinant protein of human ACMSD

Purification/Format

Affinity purification

Background

The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.
Price
916,00 €
you need any help?

Please contact:

Dr. Simone Bauer

Tel. +49 (0) 6221 71415 16

info@biocat.com

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