Rabbit anti-ABI3BP Polyclonal Antibody

Specifications
Type:Primary Antibody
Clonality:Polyclonal
Host:Rabbit
Reactivity:Human
Isotype:IgG
Label:Unconjugated
Concentration:0.7 mg/mL
Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Additional Information
Synonyms:ABI gene family member 3 (NESH) binding protein, ABI gene family member 3 binding protein, ABI gene family member 3-binding protein, ABI3BP, FLJ41743, FLJ41754, Nesh binding protein, Nesh BP, Nesh-binding protein, NeshBP, Target of Nesh SH3, Target of Nesh-SH3, Tarsh, TARSH
UniProt ID:Q7Z7G0

Applications

IHC, ELISA

Recommended Dilution

IHC 1:50-1:200

Immunogen

Recombinant protein of human ABI3BP

Purification/Format

Affinity purification

Background

A target of NESH-SH3/Abi3bp (TARSH) was originally identified as an SH3 domain-binding molecule of the NESH-SH3/Abi3 protein that is involved in Rac-dependent actin polymerization. In recent studies, TARSH gene expression was dramatically induced in mouse embryonic fibroblasts (MEFs) replicative senescence and suppressed in human lung carcinoma specimens and thyroid carcinomas. However, the molecular mechanism underlying the regulation of TARSH in tumorigenesis remains unclear.
Price
314,00 €
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