Rabbit anti-ABCG2 Polyclonal Antibody

Specifications
Type:Primary Antibody
Clonality:Polyclonal
Host:Rabbit
Reactivity:Human
Isotype:IgG
Label:Unconjugated
Concentration:1 mg/mL
Buffer:PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Additional Information
Synonyms:ABC transporter, ABC15, ABCG 2, ABCG2, ABCG2, ABCP, ATP binding cassette sub family G (WHITE) member 2, ATP binding cassette transporter G2, ATP-binding cassette sub-family G member 2, BCRP, BCRP1, BMDP, Breast cancer resistance protein, CD338, CDw338, CDw338 antigen, EST157481, GOUT1, MGC102821, Mitoxantrone resistance associated protein, Mitoxantrone resistance-associated protein, MRX, Multi drug resistance efflux transport ATP binding cassette sub family G (WHITE) member 2, MXR, MXR1, Placenta specific ATP binding cassette transporter, Placenta specific MDR protein, Placenta-specific ATP-binding cassette transporter, UAQTL1
Gene Symbol:ABCG2
Organism:Homo sapiens
Gene ID:9429
UniProt ID:Q9UNQ0

Applications

WB, IHC-p, ELISA

Recommended Dilution

WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000

Immunogen

Synthesized peptide derived from the Internal region of human ABCG2.

Purification/Format

Affinity purification

Background

Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.
Price
314,00 €
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