Rabbit anti-ABCC2 Polyclonal Antibody
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Clonality: | Polyclonal |
| Host: | Rabbit |
| Reactivity: | Human |
| Isotype: | IgG |
| Label: | Unconjugated |
| Concentration: | 0.6 mg/mL |
| Buffer: | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Additional Information | |
|---|---|
| Synonyms: | ABC30, abcC2, ATP binding cassette sub family C (CFTR/MRP) member 2, ATP binding cassette subfamily C member 2, ATP-binding cassette sub-family C member 2, Canalicular multidrug resistance protein, Canalicular multispecific organic anion transporter 1, CMOAT, CMOAT1, cMRP, DJS, KIAA1010, MRP 2, MRP2, Multidrug resistance associated protein 2, Multidrug resistance-associated protein 2 |
| UniProt ID: | Q92887 |
Applications
IHC, ELISA
Recommended Dilution
IHC 1:30-150, ELISA 1:2000-10000
Immunogen
Synthetic peptide of human ABCC2
Purification/Format
Affinity purification
Background
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia.
- Catalog Number
RD79668A-120-RDB - Supplier
Reddot Biotech - Size
- Shipping
Blue Ice
Price
602,00 €
