Rabbit anti-AARS2 Polyclonal Antibody

Specifications
Type:Primary Antibody
Clonality:Polyclonal
Host:Rabbit
Reactivity:Human, Mouse, Rat
Isotype:IgG
Label:Unconjugated
Concentration:0.4 mg/mL
Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Additional Information
Synonyms:AARS 2, AARS2, AARSL, Alanine tRNA ligase 2 mitochondrial, Alanine tRNA ligase, Alanyl tRNA synthetase 2 mitochondrial, Alanyl tRNA synthetase like, AlaRS, bA444E17.1, COXPD8, Gm89, KIAA1270, LKENP, MGC69820, MT ALARS, MTALARS, Probable alanyl tRNA synthetase mitochondrial, RP11-444E17.1
UniProt ID:Q5JTZ9

Applications

WB, IHC, ELISA

Recommended Dilution

WB 1:500-1:2000, IHC 1:50-1:200

Immunogen

Recombinant protein of human AARS2

Purification/Format

Affinity purification

Background

The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain
Price
314,00 €
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