PROTAC Mcl1 degrader-1
| Specifications | |
|---|---|
| CAS Number: | 2163793-38-0 |
| Formula: | C45H45BrN6O8S |
| Molecular Weight: | 909.84 |
Description
PROTAC Mcl1 degrader-1 induces the ubiquitination and proteasomal degradation of Mcl-1 by introducing the E3 ligase cereblon (CRBN)-binding ligand pomalidomide to Mcl-1 inhibitor S1-6 with μM-range affinity. PROTAC Mcl1 degrader-1, a proteolysis targeting chimera (PROTAC), is a potently and selectively Mcl-1 inhibitor with an IC50 of 0.78 μM.
Price
80,00 €
