PDK1/PDHK1 Polyclonal Antibody
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Clonality: | Polyclonal |
| Host: | Rabbit |
| Reactivity: | Human, Mouse, Rat |
| Isotype: | IgG |
| Label: | Unconjugated |
| Concentration: | 1mg/mL |
| Buffer: | PBS with 0.05% proclin300,50% glycerol,pH7.3. |
| Additional Information | |
|---|---|
| Synonyms: | PDK1 |
| UniProt ID: | Q15118 |
Applications
WB, IF
Recommended Dilution
WB 1:500-1:1000, IF 1:50-1:200
Immunogen
A synthetic peptide of human PDK1/PDHK1
Purification/Format
Affinity purification
Background
Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene.
Price
313,00 €
