N-cadherin Polyclonal Antibody
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Clonality: | Polyclonal |
| Host: | Rabbit |
| Reactivity: | Human, Mouse, Rat |
| Isotype: | IgG |
| Label: | Unconjugated |
| Concentration: | 200 μg/mL |
| Buffer: | PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4 |
| Additional Information | |
|---|---|
| Synonyms: | CADH2, Cadherin 2, Cadherin 2 N cadherin neuronal, Cadherin 2 type 1, Cadherin 2 type 1 N cadherin neuronal, Cadherin 2, type 1, N-cadherin (neuronal), Cadherin-2, Cadherin2, Calcium dependent adhesion protein neuronal, CD325, CD325 antigen, CDH2, CDHN, CDw325, CDw325 antigen, N cadherin 1, N-cadherin, NCAD, Neural cadherin, OTTHUMP00000066304, OTTHUMP00000067378 |
| UniProt ID: | P19022, P15116, Q9Z1Y3 |
Applications
WB, IHC
Recommended Dilution
WB 1:500-1:2000, IHC 1:300-1:800
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse N-cadherin
Purification/Format
Affinity purification
Background
Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. N-cadherin (neural cadherin),also known as CDH2 (cadherin 2),is a classical member of the cadherin superfamily which also include E-,P-,R-,and B-cadherins. Expression of N-cadherin has been reported on various cell types including neurons,endothelial cells and cardiac myocytes . N-cadherin has functions in early brain morphogenesis,synaptogenesis and synaptic plasticity .
Product Citations
- Biswajit Das, Somya Ranjan Dash, Harun Patel, Saptarshi Sinha, Subhasmita Bhal, Subarno Paul, Chinmay Das, Rajalaxmi Pradhan, Iqrar Ahmed, Kunal Goutam, Chanakya Nath Kundu (2023) Quinacrine inhibits HIF-1α/VEGF-A mediated angiogenesis by disrupting the interaction between cMET and ABCG2 in patient-derived breast cancer stem cells PHYTOMEDICINE
- Cai Jing, Wang Yue, Wang Xinfa, Ai Zihe, Li Tianyuan, Pu Xiaohong, Yang Xin, Yao Yixing, He Junping, Cheng Steven Y., Yu Tingting, Liu Chen, Yue Shen (2023) AMPK attenuates SHH subgroup medulloblastoma growth and metastasis by inhibiting NF-κB activation Cell and Bioscience
- Das Biswajit, Sethy Chinmayee, Chatterjee Subhajit, Dash Somya Ranjan, Sinha Saptarshi, Paul Subarno, Goutam Kunal, Kundu Chanakya Nath (2023) Quinacrine inhibits cMET-mediated metastasis and angiogenesis in breast cancer stem cells Journal of Cell Communication and Signaling
- Subarno Paul, Subhajit Chatterjee, Saptarshi Sinha, Somya Ranjan Dash, Rajalaxmi Pradhan, Biswajit Das, Kunal Goutam, Chanakya Nath Kundu (2023) Veliparib (ABT-888), a PARP inhibitor potentiates the cytotoxic activity of 5-fluorouracil by inhibiting MMR pathway through deregulation of MSH6 in colorectal cancer stem cells EXPERT OPINION ON THERAPEUTIC TARGETS
- Xiaojuan Yu, Wen Peng, Yaoxing Wang, Wenjun Xu, Wentong Chen, Lei Huang, Hu Xu, Xinyu He, Sheng Wang, Qianqian Sun, Wenjie Lu, Youzhi Xu (2023) Palmitic Acid Inhibits the Growth and Metastasis of Gastric Cancer by Blocking the STAT3 Signaling Pathway Cancers
Price
365,00 €
