Mouse anti-AFP Monoclonal Antibody

Specifications
Type:Primary Antibody
Clonality:Monoclonal
Host:Mouse
Reactivity:Human
Isotype:IgG
Label:Unconjugated
Concentration:1 mg/mL
Buffer:PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Additional Information
Synonyms:Afp, AFPD, Alpha fetoglobulin, Alpha fetoprotein, Alpha fetoprotein precursor, Alpha-1-fetoprotein, Alpha-fetoglobulin, Alpha-fetoprotein, alpha-fetoprotein, Hereditary persistence of, included, FETA, FETA, Hereditary persistence of alpha fetoprotein, HPAFP
Gene Symbol:AFP
Organism:Homo sapiens
Gene ID:174
UniProt ID:P02771

Applications

WB, IHC-p, IF

Recommended Dilution

WB 1:500-1:3000, IHC 1:50-1:300, IF 1:100-1:300

Immunogen

Synthetic Peptide

Purification/Format

Protein A purification

Background

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
Price
313,00 €
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