MFN2 Polyclonal Antibody
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Clonality: | Polyclonal |
| Host: | Rabbit |
| Reactivity: | Human, Mouse, Rat |
| Isotype: | IgG |
| Label: | Unconjugated |
| Concentration: | 1 mg/mL |
| Buffer: | PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4 |
| Additional Information | |
|---|---|
| Synonyms: | CMT2A, CMT2A2, CPRP 1, CPRP1, EC 3.6.5.-, Fzo, HSG, hyperplasia suppressor gene, Hypertension related protein 1, KIAA0214, MARF, MFN 2, Mfn2, MFN2, Mitochondrial assembly regulatory factor, Mitofusin-2, Mitofusin2, Transmembrane GTPase MFN2 |
| UniProt ID: | O95140 |
Applications
WB, IHC-p
Recommended Dilution
WB 1:500-1:2000, IHC 1:100-1:300
Immunogen
Synthesized peptide derived from the Internal region of human Mfn2.
Purification/Format
Affinity purification
Background
This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.
Product Citations
- Roman Krestinin, Yulia Baburina, Irina Odinokova, Alexey Kruglov, Linda Sotnikova, Olga Krestinina (2023) The Effect of Astaxanthin on Mitochondrial Dynamics in Rat Heart Mitochondria under ISO-Induced Injury Antioxidants
- Catalog Number
E-AB-32025-20ul-ELS - Supplier
Elabscience - Size
- Shipping
Blue Ice
Price
202,00 €
