MFN1 Polyclonal Antibody

Specifications
Type:Primary Antibody
Clonality:Polyclonal
Host:Rabbit
Reactivity:Human, Mouse, Rat
Isotype:IgG
Label:Unconjugated
Concentration:0.4 mg/mL
Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Additional Information
Synonyms:Fzo homolog, Hfzo1, Hfzo2, MFN 1, Mfn1, MFN1, Mitochondrial transmembrane GTPase Fzo 1, Mitochondrial transmembrane GTPase FZO 2, Mitochondrial transmembrane GTPase FZO1B, Mitofusin 1, Mitofusin-1, Mitofusin1, MS996, Putative transmembrane GTPase, Transmembrane GTPase MFN1
Accn. No.:BC040557
UniProt ID:Q8IWA4

Applications

IHC

Recommended Dilution

IHC 1:25-1:100

Immunogen

Recombinant protein of human MFN1

Purification/Format

Affinity purification

Background

The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting. Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks
Price
202,00 €
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