MDFI Polyclonal Antibody

Specifications
Type:Primary Antibody
Clonality:Polyclonal
Host:Rabbit
Reactivity:Human, Rat
Isotype:IgG
Label:Unconjugated
Concentration:0.84 mg/mL
Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Additional Information
Synonyms:I MF, I mfa, Inhibitor of MyoD family a, Mdfi, MDFI, MyoD family inhibitor, Myogenic repressor I-mf, OTTHUMP00000016375, OTTHUMP00000016376, OTTHUMP00000196103, OTTHUMP00000196414, OTTHUMP00000196415
Accn. No.:BC007836
UniProt ID:Q99750

Applications

IHC

Recommended Dilution

IHC 1:50-1:300

Immunogen

Fusion protein of human MDFI

Purification/Format

Antigen affinity purification

Background

This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.MDFI (MyoD Family Inhibitor) is a Protein Coding gene. GO annotations related to this gene include transcription factor binding. An important paralog of this gene is MDFIC.
Price
202,00 €
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