KISS1R Polyclonal Antibody
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Clonality: | Polyclonal |
| Host: | Rabbit |
| Reactivity: | Human, Mouse, Rat |
| Isotype: | IgG |
| Label: | Unconjugated |
| Concentration: | 1mg/mL |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Applications
WB, IHC
Recommended Dilution
WB 1:500-1:1000, IHC 1:50-1:100
Immunogen
A synthetic peptide of human KISS1R
Purification/Format
Affinity purification
Background
The protein encoded by this gene is a galanin-like G protein-coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. The tissue distribution of the expressed gene suggests that it is involved in the regulation of endocrine function, and this is supported by the finding that this gene appears to play a role in the onset of puberty. Mutations in this gene have been associated with hypogonadotropic hypogonadism and central precocious puberty.
Product Citations
- Marianna Marino, Raffaella D’Auria, Elena Mele, Grazia Maria Giovanna Pastorino, Paola Di Pietro, Stefania D’Angelo, Natalia Della Rocca, Francesca Felicia Operto, Carmine Vecchione, Silvia Fasano, Riccardo Pierantoni, Andrea Viggiano, Rosaria Meccariello, Antonietta Santoro (2023) The interplay between kisspeptin and endocannabinoid systems modulates male hypothalamic and gonadic control of reproduction in vivo Frontiers in Endocrinology
Price
313,00 €
