IRF4 Polyclonal Antibody
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Clonality: | Polyclonal |
| Host: | Rabbit |
| Reactivity: | Human, Mouse |
| Isotype: | IgG |
| Label: | Unconjugated |
| Concentration: | 0.2 mg/mL |
| Buffer: | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Additional Information | |
|---|---|
| Synonyms: | Interferon regulatory factor 4, IRF 4, IRF-4, Irf4, IRF4, LSIRF, Lymphocyte specific interferon regulatory factor, Lymphocyte specific IRF, Lymphocyte-specific interferon regulatory factor, Multiple myeloma oncogene 1, MUM 1, MUM1, NF EM5, NF-EM5, NFEM5, PU.1 interaction partner, Sfpi1/PU.1 interaction partner, Transcriptional activator PIP |
| Accn. No.: | NP_002451 |
| UniProt ID: | Q15306 |
Applications
WB
Recommended Dilution
WB 1:200-1:1000
Immunogen
Synthetic peptide of human IRF4
Purification/Format
Affinity purification
Background
The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6, 14)(p25, q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.
- Catalog Number
E-AB-13342-60ul-ELS - Supplier
Elabscience - Size
- Shipping
Blue Ice
Price
263,00 €
