HDAC4 Polyclonal Antibody

Specifications
Type:Primary Antibody
Clonality:Polyclonal
Host:Rabbit
Reactivity:Human, Mouse, Rat
Isotype:IgG
Label:Unconjugated
Concentration:1 mg/mL
Buffer:PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Additional Information
Synonyms:AHO3, BDMR, EC 3.5.1.98, HA6116, HD 4, HD4, HDAC 4, HDAC A, HDAC4, HDAC4, HDACA, Histone deacetylase 4, Histone Deacetylase A, KIAA0288
UniProt ID:P56524

Applications

WB

Recommended Dilution

WB 1:500-1:2000

Immunogen

Synthesized peptide derived from human HDAC4 around the non-phosphorylation site of Ser632.

Purification/Format

Affinity purification

Background

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.
Price
202,00 €
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