Fc 11a-2

Specifications
CAS Number:960119-75-9
Formula:C16H16N2
Molecular Weight:236,31

Description

Fc 11a-2, a benzimidazole compound, is an orally active and potent NLRP3 inflammasome inhibitor. Fc 11a-2 restrains the formation of NLRP3 inflammasome by inhibiting activation of caspase-1 and thus the activation of IL-1b/IL-18. Fc 11a-2 prevents the development of Dextran sulfate sodium (DSS ; HY-116282C)-induced murine experimental colitis .
Price
2.503,00 €
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