CXCR2-IN-2
| Specifications | |
|---|---|
| CAS Number: | 1838123-21-9 |
| Formula: | C18H23ClN2O5S |
| Molecular Weight: | 414,9 |
Description
CXCR2-IN-2 is a selective, brain penetrant, and orally bioavailable CXCR2 antagonist (IC50=5.2 nM/1 nM in β-arrestin assay/CXCR2 Tango assay, respectively). CXCR2-IN-2 displays ~730-fold selectivity over CXCR1 and >1900-fold selectivity over all other chemokine receptors. CXCR2-IN-2 inhibits human whole blood Gro-α induced CD11b expression with an IC50 of 0.04 μM[1].
Price
2.823,00 €
