BCX-1898

BCX-1898, a selective cyclopentane-derived, orally active influenza virus neuraminidase inhibitor, exhibits antiviral activity by inhibiting the replication of influenza A (H1N1, H3N2, H5N1) and influenza B viruses in MDCK cells, with EC50 values ranging from <0.01 to 21 μM. It demonstrates protective effects in the mouse influenza model.