APEH Polyclonal Antibody
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Clonality: | Polyclonal |
| Host: | Rabbit |
| Reactivity: | Human, Mouse, Rat |
| Isotype: | IgG |
| Label: | Unconjugated |
| Concentration: | 0.3 mg/mL |
| Buffer: | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Additional Information | |
|---|---|
| Synonyms: | AARE, ACPH, ACPH, Acyl peptide hydrolase, Acyl-peptide hydrolase, Acylamino acid releasing enzyme, Acylamino-acid-releasing enzyme, Acylaminoacyl peptidase, Acylaminoacyl-peptidase, APEH, APH, N acylaminoacyl peptide hydrolase, OPH, Oxidized protein hydrolase |
| Accn. No.: | NP_001631 |
| UniProt ID: | P13798 |
Applications
WB, IHC
Recommended Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen
Synthetic peptide of human APEH
Purification/Format
Affinity purification
Background
This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.
- Catalog Number
E-AB-12756-20ul-ELS - Supplier
Elabscience - Size
- Shipping
Blue Ice
Price
202,00 €
