Anti-Tenascin C Antibody
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Host: | Mouse |
| Reactivity: | Human |
| Isotype: | Mouse IgG1, kappa |
| Label: | Unconjugated |
| Concentration: | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide |
Applications
FC, IF, IHC (Prediluted format)
Immunogen
Human breast carcinoma cells were used as the immunogen for the Tenascin C antibody.
Background
In Western blotting, it reacts with two bands of ~MW of 21kDa and 3kDa, identified as two isoforms of Tenascin C. Specificity of this mAb is validated by sequential immunoprecipitation with a PAb against Tenascin C. Tenascin C is a multifunctional, disulfide-linked hexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.
Price
840,00 €
