Anti-S100A9 Antibody
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Clonality: | Monoclonal |
| Clone Name: | 1D5-C11-H5 |
| Host: | Mouse |
| Reactivity: | Human |
| Label: | Unconjugated |
| Additional Information | |
|---|---|
| Accn. No.: | P06702 |
Applications
ELISA (recommended work dilution = 1:320,000)
Immunogen
Immunogen was Recombinant protein Human S1 Calcium Binding Protein A9/S1-A9. This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with the immunogen. The IgG fraction of tissue culture supernatant was purified by Protein G/A affinity chromatography.
Background
S1A9 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis, adhesion, can increase the bactericidal activity of neutrophils by promoting phagocytosis via activation of SYK, PI3K/AKT, and ERK1/2 and can induce degranulation of neutrophils by a MAPK-dependent mechanism. Predominantly found as calprotectin (S1A8/A9) which has a wide plethora of intra- and extracellular functions.
Price
209,00 €
