Anti Human DOCK8 Polyclonal Antibody

WB,ELISA

ELISA 1:1,000~100,000 Western blotting 1:100~1,000

Recombinant Protein

Antigen Affinity Purified

This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Jun 2010]