AGXT Polyclonal Antibody
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Clonality: | Polyclonal |
| Host: | Rabbit |
| Reactivity: | Human, Mouse, Rat |
| Isotype: | IgG |
| Label: | Unconjugated |
| Concentration: | 0.6 mg/mL |
| Buffer: | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Additional Information | |
|---|---|
| Synonyms: | AGT, AGT1, Agxt, AGXT1, Alanine glyoxylate aminotransferase, Alanine glyoxylate aminotransferase3, Alanine--glyoxylate aminotransferase, EC 2.6.1.44, EC 2.6.1.51, Hepatic peroxisomal alanine glyoxylate aminotransferase, Hepatic peroxisomal alanine:glyoxylate aminotransferase, L alanine glyoxylate aminotransferase 1, MS773, PH1, Serine pyruvate aminotransferase, Serine--pyruvate aminotransferase, Serine--pyruvate aminotransferase, mitochondrial, Serine:pyruvate aminotransferase, SPAT, SPT, SPYA, TLH6 |
| Accn. No.: | NP_000021 |
| UniProt ID: | P21549 |
Applications
WB
Recommended Dilution
WB 1:500-1:2000
Immunogen
Synthetic peptide of human AGXT
Purification/Format
Affinity purification
Background
Serine—pyruvate aminotransferase is an enzyme that in humans is encoded by the AGXT gene. This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. Defects in AGXT are the cause of hyperoxaluria primary type 1 (HP1), also known as primary hyperoxaluria type I (PH1) and oxalosis I. HP1 is a rare autosomal recessive inborn error of glyoxylate metabolism characterized by increased excretion of oxalate and glycolate, and the progressive accumulation of insoluble calcium oxalate in the kidney and urinary tract.
- Catalog Number
E-AB-12706-60ul-ELS - Supplier
Elabscience - Size
- Shipping
Blue Ice
Price
263,00 €
