ADRA1B Polyclonal Antibody

Specifications
Type:Primary Antibody
Clonality:Polyclonal
Host:Rabbit
Reactivity:Human, Mouse, Rat
Isotype:IgG
Label:Unconjugated
Concentration:0.3 mg/mL
Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Additional Information
Synonyms:ADA1B, ADRA 1, Adra 1b, ADRA1, ADRA1B, Adrenergic alpha 1B receptor, Adrenergic receptor alpha 1b, Adrenoceptor alpha 1B, Alpha 1 adrenergic receptor, Alpha 1B adrenoceptor, Alpha 1B adrenoreceptor, Alpha-1B adrenergic receptor, Alpha-1B adrenoceptor, Alpha-1B adrenoreceptor, Alpha1 adrenergic receptor, Alpha1B adrenergic receptor, Alpha1BAR
Accn. No.:NM_000679
UniProt ID:P35368

Applications

WB

Recommended Dilution

WB 1:200-1:1000

Immunogen

Synthetic peptide of human ADRA1B

Purification/Format

Affinity purification

Background

Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.
Price
263,00 €
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