ACTL6B Polyclonal Antibody
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Clonality: | Polyclonal |
| Host: | Rabbit |
| Reactivity: | Human, Mouse, Rat |
| Isotype: | IgG |
| Label: | Unconjugated |
| Concentration: | 0.96 mg/mL |
| Buffer: | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Additional Information | |
|---|---|
| Synonyms: | 53 kDa BRG1 associated factor B, 53 kDa BRG1-associated factor B, ACL 6B, ACL6B, ACL6B, Actin like 6, Actin like protein 6B, Actin like protein6B, Actin related protein, Actin related protein Baf53b, actin-like 6B, Actin-like protein 6B, Actin-related protein Baf53b, Actl 6, ACTL 6B, Actl6, ACTL6 B, Actl6b, Arp Na, ArpN a, ArpN alpha, ArpNa, ArpNalpha, Baf 53b, BAF53B, BRG1-associated factor 53B |
| Accn. No.: | BC020944 |
| UniProt ID: | O94805 |
Applications
WB, IHC
Recommended Dilution
WB 1:1000-1:5000, IHC 1:50-1:300
Immunogen
Fusion protein of human ACTL6B
Purification/Format
Antigen affinity purification
Background
The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila, the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. Alternative splicing results in multiple transcript variants.
- Catalog Number
E-AB-52947-60ul-ELS - Supplier
Elabscience - Size
- Shipping
Blue Ice
Price
263,00 €
