AARS Polyclonal Antibody

Specifications
Type:Primary Antibody
Clonality:Polyclonal
Host:Rabbit
Reactivity:Human, Rat
Isotype:IgG
Label:Unconjugated
Concentration:0.6 mg/mL
Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Additional Information
Synonyms:AARS, AI316495, Alanine tRNA ligase 1, cytoplasmic, Alanine tRNA ligase, Alanine tRNA ligase cytoplasmic, Alanine--tRNA ligase, Alanyl tRNA synthetase, Alanyl tRNA synthetase cytoplasmic, Alanyl-tRNA synthetase, AlaRS, C76919, CMT2N, cytoplasmic, EC 6.1.1.7, MGC37368, Renal carcinoma antigen NY REN 42, Renal carcinoma antigen NY-REN-42, SYAC
Accn. No.:NP_001596
UniProt ID:P49588

Applications

IHC

Recommended Dilution

IHC 1:50-1:200

Immunogen

Synthetic peptide of human AARS

Purification/Format

Affinity purification

Background

The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure.
Price
486,00 €
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