Claudin 6 (CLDN6) Mouse Monoclonal Antibody [Clone ID: OTI2A3]

Specifications
Type:Primary Antibody
Clonality:Monoclonal
Clone Name:OTI2A3
Host:Mouse
Reactivity:Human, Mouse, Rat
Isotype:IgG1
Label:Unconjugated
Additional Information
Synonyms:claudin 6; OTTHUMP00000159248
Gene Symbol:CLDN6
Organism:Homo sapiens
Gene ID:9074
Accn. No.:NM_021195
UniProt ID:P56747

Applications

WB

Background

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.[provided by RefSeq, Aug 2010].
  • Catalog Number
    TA506894-OR
  • Supplier
    OriGene
  • Size
  • Shipping
    Blue Ice
Price
447,00 €
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