RMC-4998
| Specifications | |
|---|---|
| CAS Number: | 2642037-07-6 |
| Formula: | C57H74N8O7 |
| Molecular Weight: | 983,25 |
Description
RMC-4998 is a molecular glue compound exhibiting potent antitumor activity, capable of forming a ternary complex with CYPA and an activated KRAS G12C mutation. Binding of CYPA to KRAS G12C impedes the interaction between activated KRAS mutants and downstream effector proteins, thus obstructing proliferative cell signaling [1].
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