RTI-7470-44
Specifications | |
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CAS Number: | 825658-63-7 |
Formula: | C19H11ClF3N5OS |
Molecular Weight: | 449,84 |
Description
RTI-7470-44 is a potent and selective human trace amine-associated receptor 1 (hTAAR1) antagonist (IC50: 8.4 nM) that crosses the blood-brain barrier. RTI-7470-44 increases the spontaneous firing rate of dopaminergic neurons in the ventral tegmental area (VTA) of the midbrain in mice. RTI-7470-44 can be used to study schizophrenia, drug addiction and Parkinson's disease (PD).
Price
1.822,00 €