Desmorpholinyl Quizartinib-PEG2-COOH
| Specifications | |
|---|---|
| CAS Number: | 2292116-14-2 |
| Formula: | C30H33N5O7S |
| Molecular Weight: | 607,68 |
Description
Desmorpholinyl Quizartinib-PEG2-COOH is a compound featuring an FLT-3 ligand and a PEG-based PROTAC linker. It is employed in the synthesis of PROTAC FLT-3 degrader 1, which serves as a degrader for the FLT-3 internal tandem duplication (ITD) through PROTAC technology. The degrader exhibits an IC50 of 0.6 nM.
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