Propargyl-PEG4-acid

Specifications
CAS Number:1415800-32-6
Synonyms:Propargyl-PEG4-acid
Formula:C12H20O6
Molecular Weight:260,28

Description

Propargyl-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of BTK-IAP PROTACs Ibrutinib -based PROTAC 2 and an analogue PROTAC 3. PROTAC 3 causes BTK degradation with a DC50 of 200 nM in THP-1 cells[1].
  • Catalog Number
    T16614-500mg-TM
  • Supplier
    TargetMol
  • Size
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