pCMV-VSV-G Retroviral Vector
Product Description
pCMV-VSV-G expresses the G glycoprotein of the vesicular stomatitis virus (VSV-G) under the control of the CMV immediate-early promoter.
VSV-G is used in pseudotyping of Moloney Murine Leukenia Virus (MMLV)-based retroviral vectors by mediating viral entry. VSV-G interacts with phospholipid components of the target cell membrane and fosters the fusion of viral and cellular membranes. VSV-G does not require a cell surface receptor and can serve as a surrogate viral envelope protein.
Use the pCMV-VSV-G vector along with the pCMV-Gag-Pol vector, the 293RTV packaging cell line and a cloning / expression vector for retrovirus production.
Product Citations
- Sušjan P, Roškar S, Hafner-Bratkovič I. (2017) The mechanism of NLRP3 inflammasome initiation: Trimerization but not dimerization of the NLRP3 pyrin domain induces robust activation of IL-1β. Biochem Biophys Res Commun.
- Yang, W. S. et al. (2016) Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis. Proc Natl Acad Sci U S A.
- Abram, M. E. et al. (2015) A cell-based strategy to assess intrinsic inhibition efficiencies of HIV-1 reverse transcriptase inhibitors. Antimicrob Agents Chemother.
- Amagai, Y. et al. (2015) A point mutation in the extracellular domain of KIT promotes tumorigenesis of mast cells via ligand-independent auto-dimerization. Sci Rep.
- Gallant, J. N. et al. (2015) EGFR kinase domain duplication (EGFR-KDD) is a novel oncogenic driver in lung cancer that is clinically responsive to afatinib. Cancer Discov.
- Catalog Number
RV-110-CB - Supplier
Cell Biolabs - Size
- Shipping
Blue Ice
Price
811,00 €
